Search results for " E. coli properties analysis"
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BioAnalysis: A Framework for Structural and Functional Robustness Analysis of Metabolic Networks
2010
The main objective of this work is to analyze metabolic networks evolution in terms of their robustness and fault tolerance capabilities. In metabolic networks, errors can be seen as random removal of network nodes, while attacks are high-connectivity-degree node deletion aimed at compromising network activity. This paper proposes a software framework, namely BioAnalysis, used to test the robustness and the fault tolerance capabilities of real metabolic networks, when mutations and node deletions affect the network structure. The performed simulations are related to the central metabolic network of the well-known E. coli single-celled bacterium and involve either hub nodes or non-hub nodes,…